Peptide Reference
Semax
Semax
A synthetic peptide derived from ACTH (adrenocorticotropic hormone) developed in Russia. Known for cognitive enhancement, neuroprotection, and mood elevation without hormonal effects.
Status
approved
Category
cognitive
Typical cost
$40-100/vial (10mg)
Mechanism
Modulates expression of neurotrophic factors (BDNF, NGF), enhances brain-derived neurotrophic factor, improves cerebral circulation, and modulates neurotransmitter systems including dopamine and serotonin.
Potential benefits
- Enhanced focus and concentration
- Improved memory
- Neuroprotection
- Reduced anxiety
- Better mental clarity
- Stroke recovery support
Reported side effects
- Mild headache
- Irritation (intranasal)
- Overstimulation (rare)
- Sleep changes
Common dosing references
intranasal
100-300mcg · Daily
2-4 weeks
subcutaneous
200-500mcg · Daily
2-4 weeks
Research notes
Semax in cognitive impairment
2010
Demonstrated significant improvement in attention, memory, and mental performance in Russian clinical studies
Regulatory and sourcing notes
Approved in Russia and Ukraine for cognitive impairment and stroke recovery. Research chemical in US. Not FDA-approved.
Russian pharmaceutical product or research chemical. Verify source authenticity. Intranasal spray most common administration.
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