Peptide Reference

Dihexa

Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide)

A potent nootropic peptide analog of angiotensin IV with exceptional cognitive-enhancing and neurogenic properties. Seven orders of magnitude more potent than BDNF.

Status

research

Category

cognitive

Typical cost

$100-200/vial (10mg)

Mechanism

Potent activator of hepatocyte growth factor (HGF) with exceptional affinity for HGF receptors. Promotes synaptogenesis, neurogenesis, and enhances cognitive function far beyond other nootropics.

Potential benefits

  • Extreme potency
  • Neurogenesis
  • Synaptogenesis
  • Cognitive enhancement
  • Memory improvement

Reported side effects

  • Limited human data
  • Potentially too powerful
  • Unknown long-term effects
  • High risk experimental

Common dosing references

subcutaneous

8-20mcg · Daily

4-8 weeks

Research notes

Dihexa HGF activation

2012

Demonstrated 7 orders of magnitude greater potency than BDNF for synaptogenesis

Dihexa Alzheimer's potential

2013

Reversed cognitive deficits in Alzheimer's animal models

Regulatory and sourcing notes

Research chemical only. Not FDA-approved. Extremely potent experimental nootropic.

Research peptide. Extremely potent. Very experimental. High risk/reward profile.

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