Peptide Reference
BPC-157
Body Protection Compound 157
A pentadecapeptide derived from human gastric juice with potent healing and protective properties. Known as the 'body protection compound,' it accelerates tissue regeneration and has remarkable gut-healing capabilities.
Status
research
Category
healing
Typical cost
$30-80/vial (5mg)
Mechanism
Promotes angiogenesis, upregulates growth hormone receptors, modulates nitric oxide synthesis, and activates the FAK-paxillin pathway for tissue repair. Increases expression of genes involved in collagen formation and wound healing.
Potential benefits
- Accelerated wound healing
- Gut lining repair
- Tendon and ligament recovery
- Reduced inflammation
- Neuroprotective effects
- Improved bone healing
- Enhanced blood vessel formation
- Rapid tendon healing
- Gut protection
- Muscle repair
- Ligament healing
- Anti-inflammatory
- Systemic healing
Reported side effects
- Nausea (rare)
- Injection site irritation
- Headache (uncommon)
- Dizziness (rare)
- Hot flashes (rare)
- Mild nausea
- Injection site reactions
- Fatigue
- Headache
Common dosing references
subcutaneous
250-500mcg · 1-2x daily
4-8 weeks
oral
500mcg · 1-2x daily
4-8 weeks
subcutaneous
200-500mcg · Daily
4-8 weeks
oral
500mcg-1mg · Daily
4-8 weeks
Research notes
BPC 157 and its role in tissue healing
2018
Demonstrated accelerated healing of muscle, tendon, and bone injuries in animal models with significant reduction in healing time
Gastric protective effects of BPC-157
2016
Showed protective effects against NSAID-induced gastric lesions and promoted healing of gastric ulcers
BPC-157 tendon healing
2010
Achilles tendon healing accelerated to near-normal levels in rats
BPC-157 GI protection
1997
Protected against NSAID-induced gastric lesions
Regulatory and sourcing notes
Not FDA-approved. Available as a research peptide. Previously available from compounding pharmacies but FDA has moved to restrict. Status varies internationally.
Available from research peptide suppliers. Quality varies significantly — verify third-party COA testing. Oral bioavailability debated; subcutaneous preferred for systemic effects.
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