Peptide Reference
KPV
Lysine-Proline-Valine
A tripeptide consisting of lysine, proline, and valine. A fragment of alpha-MSH with potent anti-inflammatory properties, particularly effective for gut health and skin conditions.
Status
research
Category
healing
Typical cost
$40-90/vial (10mg)
Mechanism
Modulates inflammatory cytokine production, reduces NF-kB activation, and promotes wound healing. Acts on melanocortin receptors to reduce inflammation without the pigmentation effects of full alpha-MSH.
Potential benefits
- Reduced gut inflammation
- Improved IBD symptoms
- Accelerated wound healing
- Skin condition improvement
- Anti-inflammatory effects
- Immune modulation
Reported side effects
- Mild nausea
- Injection site reactions
- Headache (rare)
Common dosing references
subcutaneous
200-500mcg · Daily
4-8 weeks
oral
500mcg-1mg · Daily
4-8 weeks
Research notes
KPV and inflammatory bowel disease
2017
Demonstrated significant reduction in colitis symptoms and inflammatory markers in animal models
Regulatory and sourcing notes
Research chemical only. Not FDA-approved. Available from peptide research suppliers.
Research peptide only. Often used in combination with BPC-157 for gut healing protocols.
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