Peptide Reference

TB-500

Thymosin Beta-4 Fragment

A synthetic version of Thymosin Beta-4, a naturally occurring peptide involved in cell migration, wound healing, and tissue regeneration. The active fragment of the full Thymosin Beta-4 protein.

Status

research

Category

healing

Typical cost

$40-100/vial (10mg)

Mechanism

Promotes actin upregulation and cell migration. Stimulates angiogenesis, reduces inflammation, and enhances tissue regeneration through cellular migration to injury sites. Improves flexibility and reduces scar tissue formation.

Potential benefits

  • Accelerated wound healing
  • Improved flexibility
  • Reduced inflammation
  • Enhanced tissue repair
  • Heart tissue protection
  • Muscle recovery
  • Scar reduction
  • Accelerated healing
  • Tissue regeneration
  • Wound repair

Reported side effects

  • Injection site reactions
  • Headache
  • Fatigue (uncommon)
  • Nausea (rare)
  • Fatigue
  • Banned in sports

Common dosing references

subcutaneous

2-5mg · 2x weekly

4-6 weeks

subcutaneous

2mg · 2-3x weekly maintenance

Ongoing

subcutaneous

2-5mg · 2x weekly

4-8 weeks

subcutaneous (loading)

5-10mg · Weekly

2 weeks, then maintenance

Research notes

Thymosin Beta-4 and wound healing

2015

Demonstrated significant acceleration of wound closure and tissue regeneration in animal models

TB-4 in cardiac repair

2017

Showed cardioprotective effects and improved healing after myocardial injury

TB-500 wound healing

1999

Accelerated wound healing and tissue repair in animal models

TB-500 anti-inflammatory

2004

Reduced inflammatory markers and cytokines

Regulatory and sourcing notes

Not FDA-approved. Classified as research chemical. Not available from legitimate compounding pharmacies in the US.

Research peptide only. Verify purity through third-party testing. Often sold in combination with BPC-157 as 'healing stack.'

Find peptide-aware clinics

Use location pages to compare clinics with peptide therapy signals and verify clinical oversight before treatment.

Search Local Clinics