GLP-1 & Medical Weight Loss in South Carolina
189 clinics, medical spas, and weight-loss practices across 40 South Carolina cities — led by Columbia, Fort Mill, Lexington. 1 listings document GLP-1, medication, or peptide treatment directly; the other 188 are broader weight-loss and wellness practices, so confirm medication availability when you call. Statewide telehealth options are included below.
Providers
189
Cities Covered
40
Avg. Google Rating
4.8 ★
174 rated clinics
Telehealth Options
7
available statewide
Highest Rated
Top-rated weight-loss clinics in South Carolina
Ranked by Google rating weighted by review volume. Not every listing documents GLP-1 treatment — confirm current medication availability and pricing directly with the clinic.
Columbia · Wellness Center · Day Spa
4.9 · 685 reviews
Lexington · Weight Loss Service · Holistic Medicine Practitioner
4.9 · 550 reviews
West Columbia · Weight Loss Service · Medical Spa
4.8 · 576 reviews
Columbia · Weight Loss Service · Beauty Salon
5.0 · 412 reviews
Mt Pleasant · Wellness Center · Medical Spa
5.0 · 375 reviews
North Augusta · Weight Loss Service · Doctor
4.9 · 304 reviews
West Columbia · Weight Loss Service · Family Practice Physician
4.9 · 287 reviews
SeraVia
Clinical GLP-1 Support
Clinically formulated to reduce nausea, fatigue, and GI issues during GLP-1 treatment.
Free Guide
Compare GLP-1 prices before you pick a South Carolina clinic
Get the free 2026 Cost Guide — the true monthly costs, membership fees, and pharmacy sourcing of the top telehealth GLP-1 providers, so you know a fair price before you call anyone.
Free. No spam. Unsubscribe anytime. From GLP1Search.
No Clinic Nearby?
Online GLP-1 providers serving all of South Carolina
These licensed telehealth companies evaluate you online and ship medication to any South Carolina address. Published pricing shown; verify current rates on their sites.
| Provider | Membership | Medication Cost | Pharmacy |
|---|---|---|---|
| Ro | $145/month | Starting at $149/mo | 503A |
| Hims | N/A | $134 | 503B |
| Mochi Health | $39/month | Compounded Semaglutide: $99/month or Compounded Tirzepatide: $199/month | 503A |
| Henry Meds | N/A | N/A | Undisclosed |
| Sesame | $50 | 149/month | Undisclosed |
| Form Health | $299 | $299 | 503A |
| Weight Watchers Clinic | $84-$149 | $84-$149 | Undisclosed |
What GLP-1 treatment costs in South Carolina
Most South Carolina clinics price GLP-1 programs one of two ways: a monthly membership that bundles the visit, medication, and follow-ups (typically $250–$500/month for compounded semaglutide, more for tirzepatide), or à-la-carte visit fees plus a pharmacy bill. Brand-name Ozempic, Wegovy, Mounjaro, or Zepbound without insurance coverage generally runs $900–$1,400 per month at retail.
Before committing, compare three things: who supervises treatment (physician, NP, or PA, and how often you're seen), where the medication comes from (a licensed 503A/503B compounding pharmacy or brand-name supply — ask for the pharmacy's name), and the all-in monthly cost at your maintenance dose, since many programs advertise a starting-dose price that rises as you titrate up.
In-person clinics in Columbia, Fort Mill, Lexington tend to include labs and body-composition tracking that telehealth skips; telehealth tends to win on price and convenience. Neither is categorically better — it depends on whether you want hands-on monitoring or the lowest sustainable monthly cost.
Run a clinic in South Carolina?
Claim your listing free — pricing, sourcing, booking details.
All covered cities in South Carolina
GLP-1 in South Carolina: common questions
How much does semaglutide cost here?
Roughly $150–$500/month for compounded semaglutide through a clinic or telehealth provider depending on dose and program structure. Brand-name Ozempic or Wegovy without insurance typically runs $900–$1,400/month.
Can I get GLP-1s online in South Carolina?
Yes — licensed telehealth providers including Ro, Hims, Mochi Health, Henry Meds, and Sesame serve South Carolina residents with online evaluation and home delivery. See the comparison table above.
What should I ask a clinic before starting?
Who supervises treatment and how often you're seen; which pharmacy supplies the medication (name and 503A/503B status); the all-in monthly cost at your maintenance dose; and what happens with side effects or dose changes between visits.
Free Guide
Still comparing South Carolina options?
Take the 2026 Cost Guide with you — the true monthly costs, membership fees, and pharmacy sourcing of the top telehealth GLP-1 providers, free by email.
Free. No spam. Unsubscribe anytime. From GLP1Search.