What is the difference between daily and weekly GLP-1 injections?

Liraglutide (Saxenda/Victoza) requires daily subcutaneous injections, while semaglutide and tirzepatide are administered weekly. The weekly formulations use advanced molecular engineering with fatty acid side chains that bind to albumin, extending their half-life. Daily injections may provide more stable blood levels but require more commitment. Weekly options offer convenience and better adherence rates. Clinical outcomes are generally superior with weekly semaglutide compared to daily liraglutide. Most patients strongly prefer weekly dosing, which is now the standard for new GLP-1 prescriptions.