Does the dose affect how much weight I lose?

Yes, higher doses of GLP-1 medications produce greater weight loss on average. Semaglutide shows dose-dependent effects: 0.5mg produces ~10% weight loss, 1.0mg ~12-14%, and 2.4mg ~15-17%. Tirzepatide demonstrates even stronger dose-response: 5mg produces ~15% loss, 10mg ~19%, and 15mg ~22%. However, individual responses vary - some patients lose significant weight on lower doses, while others need maximum doses for meaningful results. Higher doses also increase side effect risk, so finding the optimal balance is important. The standard approach titrates upward monthly until reaching the target dose or maximum tolerated dose based on side effects. Never increase dose faster than prescribed to chase weight loss.