Peptide Reference
Kisspeptin-10
Kisspeptin-10
A decapeptide that stimulates GnRH release from the hypothalamus, triggering the reproductive hormone cascade. Key regulator of puberty, fertility, and reproductive function.
Status
research
Category
sexual health
Typical cost
$80-200/vial (5mg)
Mechanism
Binds to GPR54 receptors on GnRH neurons, stimulating pulsatile GnRH release, which triggers LH and FSH secretion from the pituitary. Essential for reproductive hormone production.
Potential benefits
- Enhanced fertility
- Increased testosterone
- Improved libido
- Reproductive health support
- Potential infertility treatment
- Restores fertility
- Natural testosterone boost
- Preserves spermatogenesis
- Regulates ovulation
- No testicular shutdown
Reported side effects
- Injection site reactions
- Mood changes
- Acne
- Headache
- Potential desensitization
- Limited data
- Variable response
- Requires precise dosing
Common dosing references
intravenous
1-6mcg/kg · Single dose or infusion
Per protocol
subcutaneous
100-300mcg · Daily
4-8 weeks
subcutaneous
1-3mcg/kg · 2-3x weekly
8-12 weeks
Research notes
Kisspeptin in hypogonadism
2011
Demonstrated ability to stimulate testosterone production in men with hypogonadotropic hypogonadism
Kisspeptin and fertility
2020
Successfully restored fertility in men with hypogonadotropic hypogonadism
Kisspeptin vs hCG
2021
More natural hormone profile than exogenous testosterone
Regulatory and sourcing notes
Research chemical only. Under investigation for infertility and hypogonadism. Not FDA-approved.
Research peptide only. Specialized use for fertility optimization. Requires medical supervision.
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