Peptide Reference

Sermorelin

Sermorelin Acetate

A growth hormone releasing hormone (GHRH) analog that stimulates the pituitary to produce and secrete growth hormone. FDA-approved for diagnosing and treating growth hormone deficiency in children.

Status

approved

Category

growth hormone

Typical cost

$300-500/month (prescription)

Mechanism

Binds to GHRH receptors in the pituitary gland, stimulating the synthesis and pulsatile release of endogenous growth hormone. Preserves the natural feedback mechanisms, reducing risk of excessive GH production.

Potential benefits

  • Increased growth hormone
  • Improved body composition
  • Better sleep quality
  • Enhanced recovery
  • Increased bone density
  • Improved immune function
  • FDA-approved
  • Natural GH pulsatility
  • No GH shutdown
  • Diagnostic utility
  • Well-studied

Reported side effects

  • Injection site reactions
  • Headache
  • Flushing
  • Dizziness
  • Sleepiness
  • Nausea
  • Short half-life

Common dosing references

subcutaneous

0.2-0.3mg · Daily at bedtime

3-6 months

Research notes

Sermorelin in GH deficiency

1997

FDA approval based on effective stimulation of GH release with good safety profile

Sermorelin GH stimulation

1997

FDA approval based on efficacy in GH deficiency

Regulatory and sourcing notes

FDA-approved for growth hormone deficiency diagnosis and treatment. Available by prescription.

Prescription only. Compounded versions available from specialty pharmacies.

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