Peptide Reference
DSIP
Delta Sleep-Inducing Peptide
A naturally occurring peptide isolated from rabbit brains that promotes sleep and reduces stress. Nine amino acids with unique sleep-modulating properties.
Status
research
Category
cognitive
Typical cost
$40-90/vial (5mg)
Mechanism
Modulates GABAergic and glutamatergic neurotransmission to promote sleep. Reduces cortisol and stress hormones. May modulate circadian rhythms through interaction with melatonin systems.
Potential benefits
- Improved sleep quality
- Reduced stress/anxiety
- Better recovery
- Lower cortisol
- Non-sedating
- Deep sleep enhancement
- Delta wave promotion
- Stress modulation
- No next-day grogginess
- Mood stabilization
Reported side effects
- Mild headache
- Vivid dreams
- Daytime drowsiness (rare)
- Limited data
- Variable response
- Headache
Common dosing references
subcutaneous
100-300mcg · Daily or before bed
4-8 weeks
subcutaneous
100-300mcg · Daily evening
8-12 weeks
Research notes
DSIP and sleep architecture
1995
Demonstrated improvements in sleep quality and duration in limited studies
DSIP sleep enhancement
1977
Improved delta sleep and normalized sleep patterns in research subjects
DSIP stress response
1980
Modulated cortisol patterns and stress response
Regulatory and sourcing notes
Research chemical only. Not FDA-approved. Limited clinical data despite decades of research.
Research peptide. Quality varies. Short half-life requires daily dosing.
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