Semax
Semax
A synthetic peptide derived from ACTH (adrenocorticotropic hormone) developed in Russia. Known for cognitive enhancement, neuroprotection, and mood elevation without hormonal effects.
Typical Cost
$40-100/vial (10mg)
Status
Research
Peptide Profile
Semax
Mechanism of Action
Modulates expression of neurotrophic factors (BDNF, NGF), enhances brain-derived neurotrophic factor, improves cerebral circulation, and modulates neurotransmitter systems including dopamine and serotonin.
Common Dosages
intranasal
100-300mcg
Daily · 2-4 weeks
subcutaneous
200-500mcg
Daily · 2-4 weeks
Benefits
Enhanced focus and concentration
Improved memory
Neuroprotection
Reduced anxiety
Better mental clarity
Stroke recovery support
Side Effects
Mild headache
Irritation (intranasal)
Overstimulation (rare)
Sleep changes
Key Research
Semax in cognitive impairment
Demonstrated significant improvement in attention, memory, and mental performance in Russian clinical studies
Regulatory Status
Approved in Russia and Ukraine for cognitive impairment and stroke recovery. Research chemical in US. Not FDA-approved.
Contraindications
- ⚠Pregnancy/breastfeeding
- ⚠Acute psychosis
- ⚠Severe hypertension
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