KPV
Lysine-Proline-Valine
A tripeptide consisting of lysine, proline, and valine. A fragment of alpha-MSH with potent anti-inflammatory properties, particularly effective for gut health and skin conditions.
Typical Cost
$40-90/vial (10mg)
Status
Research
Peptide Profile
KPV
Mechanism of Action
Modulates inflammatory cytokine production, reduces NF-kB activation, and promotes wound healing. Acts on melanocortin receptors to reduce inflammation without the pigmentation effects of full alpha-MSH.
Common Dosages
subcutaneous
200-500mcg
Daily · 4-8 weeks
oral
500mcg-1mg
Daily · 4-8 weeks
Benefits
Reduced gut inflammation
Improved IBD symptoms
Accelerated wound healing
Skin condition improvement
Anti-inflammatory effects
Immune modulation
Side Effects
Mild nausea
Injection site reactions
Headache (rare)
Key Research
KPV and inflammatory bowel disease
Demonstrated significant reduction in colitis symptoms and inflammatory markers in animal models
Regulatory Status
Research chemical only. Not FDA-approved. Available from peptide research suppliers.
Contraindications
- ⚠Pregnancy/breastfeeding
- ⚠Active infections
KPV's gut-healing properties pair well with SeraVia Gut+ Balance for GLP-1 users managing digestive side effects and gut inflammation.
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Search Providers →Disclaimer: This information is for educational and research purposes only. Peptides described here may not be FDA-approved for human use. Always consult a qualified healthcare provider before using any peptide product. GLP1Search does not sell peptides.