Ipamorelin
Ipamorelin Acetate
A growth hormone releasing peptide (GHRP) that selectively stimulates the pituitary to release growth hormone without affecting cortisol or prolactin. Known as the cleanest GHRP with minimal side effects.
Typical Cost
$40-80/vial (5mg)
Status
Research
Peptide Profile
Ipamorelin
Mechanism of Action
Binds to ghrelin receptors in the hypothalamus and pituitary, triggering pulsatile growth hormone release. Does not significantly raise cortisol or prolactin unlike other GHRPs. Maintains natural GH pulsatility.
Common Dosages
subcutaneous
100-300mcg
1-3x daily · 8-12 weeks
Benefits
Increased growth hormone
Fat loss
Muscle preservation
Improved sleep
Faster recovery
Anti-aging effects
Better skin quality
Side Effects
Increased hunger
Headache
Water retention
Injection site reactions
Numbness/tingling
Key Research
Ipamorelin growth hormone stimulation
Demonstrated selective GH release without cortisol or prolactin elevation in clinical studies
Ipamorelin in growth hormone deficiency
Effective at increasing IGF-1 levels with favorable safety profile
Regulatory Status
Not FDA-approved. Available by prescription in some countries for specific indications. Research chemical status in US.
Contraindications
- ⚠Active cancer
- ⚠Diabetic retinopathy
- ⚠Pregnancy/breastfeeding
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