What should my goal weight be on GLP-1 medications?

Goal setting on GLP-1s should focus on health improvements rather than arbitrary numbers. A 5-10% weight loss produces significant metabolic benefits: improved blood pressure, better glucose control, reduced inflammation, and lower cardiovascular risk. Many patients aim for 15-20% loss based on clinical trial averages. Set process goals (protein intake, exercise frequency, medication adherence) rather than just outcome goals. Consider your weight history - if you've never maintained below a certain weight, that may indicate your body's defended set point. Some patients achieve 'super responder' status with 25-30%+ loss, but this shouldn't be expected. Work with your provider to set individualized goals based on your starting BMI, health conditions, and personal preferences. Adjust goals as you progress and learn how your body responds.