Accidental overdose of GLP-1 medications can cause severe gastrointestinal symptoms but is rarely life-threatening. Symptoms of overdose include: severe nausea and vomiting, extreme diarrhea, severe abdominal pain, and potentially dangerous dehydration. There is no specific antidote for GLP-1 overdose. Management is supportive: hydration (oral if possible, IV if severe), anti-nausea medications, and monitoring. Contact poison control (1-800-222-1222 in the US) and seek medical attention if you've taken significantly more than prescribed. If you accidentally took your weekly dose twice in one week, you may have intensified side effects but serious harm is unlikely. Do not take additional doses to 'make up' for missed doses - this increases overdose risk. Keep medications in their original packaging with clear labels to prevent confusion. If you have children in the home, store medications locked away - while GLP-1s aren't controlled substances, pediatric ingestion requires immediate medical evaluation. Most overdose situations resolve with supportive care within 24-48 hours.
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