Adequate sleep (7-9 hours nightly) is crucial during GLP-1 therapy for multiple reasons. Poor sleep increases hunger hormones and decreases satiety hormones, counteracting the medication's appetite suppression. Growth hormone release during deep sleep supports muscle preservation during weight loss. Sleep deprivation increases cortisol, promoting fat storage and muscle breakdown. Most weight loss plateaus and muscle loss occur in sleep-deprived individuals. Many GLP-1 users report improved sleep quality as weight decreases and sleep apnea improves. Establish consistent sleep and wake times, even on weekends. Create a cool, dark, quiet sleep environment. Avoid screens 1 hour before bed. Limit caffeine after noon. If you're waking frequently to urinate (common with improved glucose control and fluid intake), discuss timing with your provider. Consider tracking sleep quality with wearables - improvements often precede scale victories.
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